Do pharmacies need to retain IMP due for destruction (patient returns or expired stock) until a monitor can check these at a site visit before destroying?
You can go ahead and destroy these. You just need to ensure this is documented appropriately (on the patient dispensing log or the destruction log).
What do I do with remaining dasatinib not required?
Destroy as per local trust procedures, complete the 'SPIRIT 2 destruction log' and email a copy to the SPIRIT office.
What happens after March 2018 with patients receiving dasatinib?
Recent NICE guidance have recommended first and second line dasatinib for routine use in the NHS (see link here). We plane to transistion patients from trial stock to NHS stock after March 2018